About 100 years ago, humanity learned to see with the help of electrons. In 1924, Louis de Broglie posited that
like light particles
electrons have wave properties. In 1927, the U.S. physicists Davisson and Germer provided experimental proof of this.
The article from Phys.org discusses a breakthrough in high-resolution microscopy by a team of researchers from the University of Illinois Urbana-Champaign. They have developed new standards for calibrating super-resolution fluorescence microscopy, which allows for imaging at resolutions beyond the diffraction limit of light. This advancement is crucial for accurately measuring the size and distance of biological structures at the nanoscale. The team introduced a method using DNA origami nanostructures as calibration tools, which provide precise control over the placement of fluorescent molecules. This calibration technique not only enhances the accuracy of measurements but also helps in comparing results across different labs and microscopy techniques. The implications of this work are significant for fields like cell biology, neuroscience, and materials science, where understanding structures at the molecular level is essential.
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